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Hyperglycemia in type II diabetes?


The cause of Type II diabetes is insulin resistant. Why doctor priscribe medicine that release more insulin to bring the glucose level down and to make the patient more resistant to insulin?

Hi
I have been a diabetic for 22 years and just found this website about 3months ago. This is a great website for diabetics.
http://www.diabetesforums.com/

Because the meds are insulin analogues, not true insulin.

it is not insulin resistance that is the cause of diabetes but the problem in its production bt the beta cells of he pancreas or its malfunction in the system. insulin is the key by which glucose enters the cells so if theres a lack in insulin or a deformity in its being , glucose cannot be absorbed by the cells and floats around in the blood making it viscous and hyperglycemic (increased blood sugar). insulin is prescribed so that the glucose can get into the cells and be metabolized.

Insulin resistance means that insulin produced by your pancreas cannot get inside fat and muscle cells to produce energy. Since the cells are not getting the insulin they need, the pancreas produces more and more. Over time, abnormally high levels of
sugar build up in the blood. This is called hyperglycemia. Many people with insulin resistance have hyperglycemia and high blood insulin levels at the same time. People who are overweight have a higher risk of insulin resistance, because fat interferes with the body's ability to use insulin.
The first goals are to eliminate the symptoms and stabilize your blood glucose levels. The ongoing goals are to prevent long-term complications and prolong your life. The primary treatment for type 2 diabetes is exercise and diet.
When diet and exercise do not help maintain normal or near-normal blood glucose levels, your doctor may prescribe medication. Some of the most common types are listed below.

* Oral sulfonylureas (like glimepiride, glyburide, and tolazamide) trigger the pancreas to make more insulin.
* Biguanides (Metformin) tell the liver to decrease its production of glucose, which increases glucose levels in the blood stream.
* Alpha-glucosidase inhibitors (such as acarbose) decrease the absorption of carbohydrates from the digestive tract, thereby lowering the after-meal glucose levels.
* Thiazolidinediones (such as rosiglitazone) help insulin work better at the cell site. In essence, they increase the cell's sensitivity (responsiveness) to insulin.
* Meglitinides (including repaglinide and nateglinide) trigger the pancreas to make more insulin in response to how much glucose is in the blood.

As, the cause of diabetes is insulin resistance, doc, may prescibe you Medications such as metformin (Glucophage庐), troglitazone (Rezulin庐), and acarbose (Precose庐), alone or in combination, which have been used to improve insulin sensitivity.

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