does the immune system and blood group influence this condition Sepsis (in Greek 危萎蠄喂蟼, putrefaction) is a serious medical condition, resulting from the immune response to a severe infection. Septicemia is sepsis of the bloodstream caused by bacteremia, which is the presence of bacteria in the bloodstream. The term septicemia is also used to refer to sepsis in general.
Treatment
Treatment
The therapy of sepsis rests on antibiotics, surgical drainage of infected fluid collections, fluid replacement and appropriate support for organ dysfunction. This may include hemodialysis in kidney failure, mechanical ventilation in pulmonary dysfunction, transfusion of blood products, and drug and fluid therapy for circulatory failure. Ensuring adequate nutrition, if necessary by parenteral nutrition, is important during prolonged illness.
Early Goal Directed Therapy (EGDT), developed at Henry Ford Hospital by E. Rivers, MD, is a systomatic approach to resuscitation that has been validated in the treatment of severe sepsis and septic shock. It is meant to be started in the Emergency Department. The theory is that one should use a step-wise approach, having the patient meet physiologic goals, to optimze cardiac preload, afterload, and contractility, thus optimizing oxygen delivery to the tissues.[4]
In EGDT, fluids are administered until the central venous pressure (CVP), as measured by a central venous catheter reachs 8-12 cm of water. If the mean arterial pressure is less than 65 mmHg or greater 90 mmHg, vasopressors or vasodilators are given as needed to reach the goal. Once these goals are met the central venous saturation (ScvO2), i.e. the oxgyen saturation of venous blood as it returns to the heart as measured at the right atrium, is optimized. If the ScvO2 is less than 70%, blood is given to reach a hemoglobin of 10 g/dl and then inotropes are added until the ScvO2 is optimized. Elective intubation may be performed to reduce oxygen demand if the ScVO2 remains low despite optimization of hemodynamics. Urine output is also monitored, with a goal of 0.5 ml/kg/h. In the original trial, mortality was cut from 46.5% in the control group to 30.5% in the intervention group. [5] The Surviving Sepsis Campaign guidelines recommends EGDT for the initial resuscitation of the septic patient with a level B strength of evidence (single randomized control trial). [6]
Most therapies aimed at the inflammatory process itself have failed to improve outcome. However, drotrecogin alfa (activated protein C, one of the coagulation factors) has been shown to decrease mortality from about 31% to about 25% in severe sepsis.[7] Low dose hydrocortisone treatment has shown promise for septic shock patients with relative adrenal insufficiency as defined by ACTH stimulation testing.[8] Toxins enter your blood stream, usually gram-negative bacteria. The latter trigger immune responses and widespread coagulation in blood vessels. High fever, chills, weakness, and sweating are followed by a drop in blood pressure. Treatment would most likely be broad spectrum antibiotics. Blood cultures will confirm the septicemia and it is very serious... Septicemia is caused by generalised infection of the bloodstream by bacteria overcoming the body's attempts to cope, and the immune response being ultimately deadly.
I don't think that blood group has much influence about it.
Cure is massive antibiotic therapy, but in recent years resistant strains of staphs and the like have made it more dicey than when it was introduced. Septicemia is the clinical name for blood poisoning
Possibly causes of Septicemia includes:
Wound infection
Surgical infection
Tooth abscess
Gall bladder infection
Appendicitis
Burns
Abscess
Other conditions that might have Septicemia as a complication may as
Anthrax
Cellulitis
Food poisoning
Gangrene
Postpartum hemorrhage
Renal carbuncle
Sepsis
Treatment for septicemia:
Specific treatment for septicemia will be determined by your physician based on:
1)age, overall health, and medical history
2)extent of the condition
3)tolerance for specific medications, procedures, or therapies
expectations for the course of the condition
Septicemia is a medical emergency that requires immediate medical attention. In most cases, treatment will involve antibiotic medication. Sepsis (putrefaction) is a serious medical condition, resulting from the immune response to a severe infection. Septicemia is sepsis of the bloodstream caused by bacteremia, which is the presence of bacteria in the bloodstream. The term septicemia is also used to refer to sepsis in general.
The immunological response that causes sepsis is a systemic inflammatory response causing widespread activation of inflammation and coagulation pathways. This may progress to dysfunction of the circulatory system and, even under optimal treatment, may result in the multiple organ dysfunction syndrome and eventually death.
Sepsis is common and also more dangerous in elderly, immunocompromised, and critically ill patients. It occurs in 1%-2% of all hospitalizations and accounts for as much as 25% of intensive care unit (ICU) bed utilization. It is a major cause of death in intensive care units worldwide, with mortality rates that range from 20% for sepsis to 40% for severe sepsis to >60% for septic shock. In the United States, sepsis is the leading cause of death in non-coronary ICU patients, and the tenth most common cause of death overall according to 2000 data from the Centers for Disease Control and Prevention.
The therapy of sepsis rests on antibiotics, surgical drainage of infected fluid collections, fluid replacement and appropriate support for organ dysfunction. This may include hemodialysis in kidney failure, mechanical ventilation in pulmonary dysfunction, transfusion of blood products, and drug and fluid therapy for circulatory failure. Ensuring adequate nutrition, if necessary by parenteral nutrition, is important during prolonged illness. |
