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What is the treatment for sepsis?????


tinfection in the bloodstream? and will you get better or will tehre be permanent damage to your body?

The therapy of sepsis rests on antibiotics, surgical drainage of infected fluid collections, fluid replacement and appropriate support for organ dysfunction. This may include hemodialysis in kidney failure, mechanical ventilation in pulmonary dysfunction, transfusion of blood products, and drug and fluid therapy for circulatory failure. Ensuring adequate nutrition鈥攑referrably by enteral feeding, but if necessary by parenteral nutrition鈥攊s important during prolonged illness.

A problem in the adequate management of septic patients has been the delay in administering therapy after sepsis has been recognized. Published studies have demonstrated that for every hour delay in the administration of appropriate antibiotic therapy there is an associated 7% rise in mortality. A large international collaboration was established to educate people about sepsis and to improve patient outcomes with sepsis, entitled the "Surviving Sepsis Campaign." The Campaign has published an evidence-based review of management strategies for severe sepsis, with the aim to publish a complete set of guidelines in subsequent years.

Early Goal Directed Therapy (EGDT), developed at Henry Ford Hospital by E. Rivers, MD, is a systematic approach to resuscitation that has been validated in the treatment of severe sepsis and septic shock. It is meant to be started in the Emergency Department. The theory is that one should use a step-wise approach, having the patient meet physiologic goals, to optimize cardiac preload, afterload, and contractility, thus optimizing oxygen delivery to the tissues.

In EGDT, fluids are administered until the central venous pressure (CVP), as measured by a central venous catheter, reaches 8-12 cm of water (or 10-15 cm of water in mechanically ventilated patients). This may require around 6 liters of isotonic crystalloid solution, rapidly administered. If the mean arterial pressure is less than 65 mmHg or greater than 90 mmHg, vasopressors or vasodilators are given as needed to reach the goal. Once these goals are met, the mixed venous oxygen saturation (SvO2), i.e. the oxgyen saturation of venous blood as it returns to the heart as measured at the vena cava, is optimized. If the SvO2 is less than 70%, blood is given to reach a hemoglobin of 10 g/dl and then inotropes are added until the SvO2 is optimized. Elective intubation may be performed to reduce oxygen demand if the SvO2 remains low despite optimization of hemodynamics. Urine output is also monitored, with a minimum goal of 0.5 ml/kg/h. In the original trial, mortality was cut from 46.5% in the control group to 30.5% in the intervention group. The Surviving Sepsis Campaign guidelines recommends EGDT for the initial resuscitation of the septic patient with a level B strength of evidence (single randomized control trial).

Most therapies aimed at the inflammation process itself have failed to improve outcome, however drotrecogin alfa (activated protein C, one of the coagulation factors) has been shown to decrease mortality from about 31% to about 25% in severe sepsis. To qualify for drotrecogin alfa, a patient must have severe sepsis or septic shock with an APACHE II score of 25 or greater and a low risk of bleeding.[11] Low dose hydrocortisone treatment has shown promise for septic shock patients with relative adrenal insufficiency as defined by ACTH stimulation testing.

antibotics it the teatment
depends on how bad you have it
some have no problems at all once they are healed

Sepsis is very serious. Treatment involves using antibiotics to get rid of the bacteria in your blood steam. The antibiotics that will be prescribed for you depends on the organism that is causing the sepsis. They have to see what antibiotic works best against it in the lab. Keep in mind that only gram negative bacteria causes sepsis and gram negative bacteria are stronger than gram positive. If the antibiotic is effective to the organism, then you will get better. If the bacteria is drug resistant, then they will have to use stronger and harsher antibiotics such as gentamycin which can damage kidneys. No one can say if you will have permanent damage because it all depends on many factors. Do you know the name of the bacteria causing the sepsis?

sepsis just means that your whole body is sick with an illness. It depends on what type of organism it is. And the doctors will also look for a "source" to the infections. Meaning, where did the infection come from, or where is it at...is it in the urine, blood, etc... then they will treat from there. The length of time of antibiotics is dependent upon the type of infection one has. Permanent damage does not usually occur, but there is always a different picture with every puzzle. So to answer your question, yes, you will get better.

IV antibiotics.

Sometimes it can lead to gangrene of the extremities in very bad cases.

There's varying degrees of sepsis.

a lot of very strong anti -biotics!!

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