What area of the world did Scarlet fever originate from?, and what is the degree of damage caused by it?

Scarlet fever is caused by a bacteria called group A streptococcus (GAS). It produces several exotoxins of which 2 (known as SSPE A and C) causes scarlet fever. This is basically a generalized rash that occurs in several areas of the body. It is also one of the 6 child hood causes of exanthum(rash). It is also known as Scarlatina (from the Italian scarlattina). Infections are common in children because they do not have antibodies against the exotoxins.

The main damage is not caused by the scarlet fever, but by the other exotoxins especially SSPE A. It can cause toxic shock that is highly fatal. GAS infections can also cause acute rheumatic fever and acute glomerulonephritis. However this is due to a component known as M proteins.

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　　Scleroderma 　　SCID 　　Sciatica 　　School Health 　　Schizophrenia 　　Scars 　　Scarlet Fever 　　Scabies 　　SARS 　　Sarcoma 　　Sarcoidosis 　　Salt 　　Salmonella Infections

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