mcrh.org
*Home>>>Sarcoma

Anyone know much about synovial sarcoma and whether it is a serious cancer?


what are the chance of a sarcoma coming back because i have been given the all clear after bieng diognosed over a year ago with synovial sarcoma to the neck.... grade 2.

What is synovial sarcoma?
Synovial sarcoma is a type of soft tissue sarcoma. Soft tissue sarcomas are cancers of the muscle, fat, fibrous tissue, blood vessels, or other supporting tissue of the body, including synovial tissue. Synovial tissue lines the cavities of joints, such as the knee or elbow, tendons (tissues that connect muscle to bone), and bursae (fluid-filled, cushioning sacs in the spaces between tendons, ligaments, and bones). Although synovial sarcoma does not have a clearly defined cause, genetic factors are believed to influence the development of this disease.

How often does synovial sarcoma occur?
Synovial sarcoma is rare. It accounts for between 5 and 10 percent of the approximately 10,000 new soft tissue sarcomas reported each year (1). Synovial sarcoma occurs mostly in young adults, with a median age of 26.5 (1). Approximately 30 percent of patients with synovial sarcoma are younger than 20. This disease occurs more often in men than in women (1).

Where does synovial sarcoma develop?
About 50 percent of synovial sarcomas develop in the legs, especially the knees. The second most common location is the arms (2). Less frequently, the disease develops in the trunk, head and neck region, or the abdomen (1, 2). It is common for synovial cancer to recur (come back), usually within the first two years after treatment. Half of the cases of synovial sarcoma metastasize (spread to other areas of the body) to the lungs, lymph nodes, or bone marrow (1).

What are the symptoms of synovial sarcoma?
Synovial sarcoma is a slow-growing tumor. Because it grows slowly, a person may not have or notice symptoms for some time, resulting in a delay in diagnosis. The most common symptoms of synovial sarcoma are swelling or a mass that may be tender or painful (1). The tumor may limit range of motion or press against nerves and cause numbness. The symptoms of synovial sarcoma can be mistaken for those of inflammation of the joints, the bursae, or synovial tissue. These noncancerous conditions are called arthritis, bursitis, and synovitis, respectively.

How is synovial sarcoma diagnosed?
The doctor may use the following procedures and tests to diagnose synovial sarcoma:

Biopsy: Tissue is removed for examination under a microscope.

Immunohistochemical analysis: Tumor tissue is tested for certain antigen and antibody interactions common to synovial sarcoma.

Ultrastructural findings: The tissue is examined using an ultramicroscope and electron microscope.

Genetic testing: Tissue is tested for a specific chromosome abnormality common to synovial sarcoma.

How is synovial sarcoma treated?
The type of treatment depends on the age of the patient, the location of the tumor, its size, its grade (how abnormal the cancer cells look under a microscope and how likely the tumor will quickly grow and spread), and the extent of the disease. The most common treatment is surgery to remove the entire tumor with negative margins (no cancer cells are found at the edge or border of the tissue removed during surgery). If the first surgery does not obtain negative tissue margins, a second surgery may be needed.

The patient may also receive radiation therapy before or after surgery to control the tumor or decrease the chance of recurrence (cancer coming back). The use of intraoperative radiation therapy (radiation aimed directly at the tumor during surgery) and brachytherapy (radioactive material sealed in needles, wires, seeds, or catheters, and placed directly into or near a tumor) are under study.

Patients may also receive chemotherapy alone or in combination with radiation therapy

Sarcomas are difficult to treat because they hardly respond to standard cancer treatments such as chemo and radiation.
However, since you were only stage 2, and probably had a surgery to remove it, there is a high chance that you are cured.

Synovial sarcoma is a type of soft tissue sarcoma. Soft tissue sarcomas are cancers of the muscle, fat, fibrous tissue, blood vessels, or other supporting tissue of the body, including synovial tissue. Synovial tissue lines the cavities of joints, such as the knee or elbow, tendons (tissues that connect muscle to bone), and bursae (fluid-filled, cushioning sacs in the spaces between tendons, ligaments, and bones). Although synovial sarcoma does not have a clearly defined cause, genetic factors are believed to influence the development of this disease.

hhhmm...my sister died from it. I guess it comes back cuz she had a tumor in the lower lobe of her left lung and they removed it, but within 2 weeks it was back in the lung and it had spread to her liver and pancreas and kidneys within 1 month. Like I said she died from it and for some reason it spread rapidly. Its not suppoded to ya know, its supposed to be a slow growing cancer but she was diagnosed in august of 2006 and she died in febuary of 2007.

YOUR DOCTOR SHOULD BE ABLE TO ANSWER YOUR QUESTION BETTER THAN ANYONE HERE

50-50
about half the cases of synovial sarcoma recur within two years. And when they do it is usually with multiple sites of metastisis.
Hang in there, I beat fibro sarcoma in my spine, you can beat this.

You really need to speak to your specialist. Sarcomas do have a habit of returning, in different parts of your body. We are currently researching this because of my friends 11 year old son. I really wouldnt take advice of this site, or any other, each sarcoma is different, and will react/re-appear in different places over different lengths of time. The only people who can advise you on this are those who are already dealing with you and your recovery.

Tags
  School Health   Schizophrenia   Scars   Scarlet Fever   Scabies   SARS   Sarcoma   Sarcoidosis   Salt   Salmonella Infections   Salivary Gland Disorders   SAD
Related information
  • Synovial Cell Sarcoma?

    Well, my dear, come on over to the Sarcoma Alliance where you will find some kindred souls!! We aren't all dealing with the same subtype of sarcoma, but we are dealing with rare and small grou...

  • Ewings sarcoma?

    Ewings Sarcoma is a very rare cancer. There is about 450 cases diagnosed per year. It also is a type of cancer that usually appears in children during growing cycle. Also, it is more common in lo...

  • Synovial Sarcoma?

    Your daughter in law should be treated by a sarcoma specialist or at a sarcoma center because this disease is so rare. The best places to find information about sarcoma is with the support groups. ...

  • How does a soft tissue sarcoma appear on a regular xray?

    Please take Panda's excellent advice and pursue this with a sarcoma specialist if possible. I would at least recommend a biopsy, based on my own sarcoma experience. I had a "probably no...

  • Paediatric Sarcoma Cancer Specialist in Uk?

    Your friend may want to consider contacting the Royal Marsden Hospital. According to their web site, their Sarcoma unit "is recognized world-wide for its strength in diagnosing and treati...

  • Kaposi Sarcoma?

    Kaposi Sarcoma is caused by the 8th kind of herpes virus (herpes simplex virus 8) and usually happens after the patient has had AIDS for a while. By the time lesions appear, it is likely that the i...

  • Kaposi's Sarcoma???!!?

    You're a little ahead of yourself. If you have a "real" sarcoma, then you likely would already have AIDS, not just HIV, and you would probably know it from illness before the sarcom...

  • Is it true that chemotherapy makes it worse when you have sarcoma cancer?

    There are over 60 different types of sarcoma and all are treated differently. So, it is difficult to respond to your question. It is not true however that sarcoma does not respond to chemotherapy. ...

  •  

    Categories--Copyright/IP Policy--Contact Webmaster