Wife 48yo f has NMO, probable lung sarcoidosis, limited vision, now devel. klebsiella oxy in hospital. what to

what to do

infection bc of 2-3 catheter lines femoral central and picc

tons of cultures / say no growth, blood and urine / lungs clear except for granulomas just found on ct scan, on Rituxan every 6 months from nmo / also have had tons of steroids last few yrs due to opric nerve attacks

on vancomycin and avelox 1-2 weeks, spiking high fevers 101ish

ok protocal / worried that other organs are infected / have infectous disease guy on board and we are in hospital

want to check to be sure we are on the right path

Thanks a lot

Is NMO neuromyelitis?

Klebsiella oxytoca is very antibiotic resistant. Ask the doctors about Claforan and Gentamicin combo, and possibly Rifampin. Also ask about the LPS-binding protein (it is a study I heard about once???) which inactivates the cell wall formation of the bacteria.

If your wife is has granulomas in her lungs, then have you tried Prednisone? Or maybe inhaled striods? That is the standard treatment for sarcoidosis I believe. If you start early enough, then the outcome is good. Most people with sarcoidosis don't even know they have it, as it is usually symptomless.

Best of luck to you both, and tell your wife that a positive mindset actually will heal her faster, and give her better chances.

Very complicated. Follow the doctors advice

It sounds like you are doing all that you can. Have faith that what is supposed to happen will happen. Be strong and love her while you still have her.