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Whats a very rare disease?


I have to do a report for my medical English class, the prompt is a research paper on some type of sickness that happens. I can't do and sort of cancer. I was hoping that i could get some good ideas, I am up for anything that is rare but any ideas are gladley appreciated. thanks

i watch house but i need one tommorow, plus there is not always a disease always on an episode on house

Try watching House. They always have weird diseases on there.
(My worst nightmare is getting a human bot fly larva. Look it up.)

Two words:
Harlequin Ichthyosis

Look it up.

aortic dissection
Cat eye syndrome
Pulmonary Hypertension

necrotizing fasciitis, or a flesh eating disease are very interesting and really nasty, try that.

Morgellons-its been in the news lately
Morgellons is by far the best known example of one of several similar conditions characterized by crawling sensations, skin problems (lesions and sores), and the finding of fibers on the skin. The more general term for a condition like this is a 鈥淔iber Disease鈥? Mary Leitao discovered it on the internet in 2002, and decided it applied to her son鈥檚 eczema She calledit 鈥淢orgellons鈥? and started an internet phenomena. Butthe exact same list of symptoms has been around for a lot longer.Of course, as the Morgellons Research Foundation points out, since these conditions resemble Delusions of Parasitosis, then similar things must have been happening at least since DP was first described over a hundred years ago. What is relatively new is the formation of groups that band together in their insistence that their conditions are caused by some unidentified parasite, toxin, or infectious agent. There are various groups, and various theories, dating back many years.The following is a brief time-line of various important points in the development of Fiber Disease organizations.
1947, in Skin Manifestations of Internal Disorders, Kurt Weiner describes DP patients who:
鈥減ersistently bring little follicular plugs, scales, or woolen fibers wrapped in paper or kept in a box to convince the doctor they have worms or insects in their skin鈥?951, Feb - Jay Traver published her paper 鈥淯nusual Scalp Dermatitis in Humans Caused by the Mite, Dermatophagoides鈥? This describes her experiences since 1934 of her own belief in infestation, but inability to get doctors to concur. While she does not mention fibers, her account is often pointed to as validation by people with the fiber disease. Later examination of her evidence concluded the few mites she found were ordinary dust mites, and Traver was in fact suffering from delusional parasitosis (see: John O鈥橠onel Alexander, 1984, Arthropods and Human Skin)
1995 - Approximate date of cases of 鈥淣CS鈥?described by Amin in 2001, below.
1995 - Approximate date that NPA started recording cases of 鈥渁n increasing number of individuals reporting lice or scabies but describing symptoms inconsistent with either of these parasites.鈥?996 - Approximate start of popular usage of the internet. From 1996 to 2007, internet usage grows from 16 million to 1093 Million. The internet is a major factor in spreading knowledge of the fiber diseases.
1998, Dec - Oldest archived version of the NUSPA web site. States:However, because the parasite appears to have so many different metamorphic features, many of which may resemble, human hair, fabric or lint (for example) turn of the century physicians wrongly assumed their patients must have been suffering from a psychosomatic illness rather than a disease.
Rashes, lesions, itching, burning sensations, track marks, scratches, and papules appear from nowhere on the surface of the skin, along with burrows under the skin, containing what the sufferer describes as 鈥渆ggs鈥? Some people complain of having symptoms in only one spot on the skin ( i.e., scalp, face, rectum, groin area) while others are infested from head to toe. Acute insomnia can also be a symptom of this disease.Black specks, iridescent crystals, microscopic hairs, wormlike creatures, hairlike creatures (the size of an eyelash to several inches long, and colors ranging from transparent to shinny black) 鈥渓intlike balls鈥?bloody and/saltlike granules and threads, have all been described as emerging from the lesions. Often clothes, bedding, carpets, furniture and cars are heavily infested, again without remedy.
1999, Feb -Postings on parasite mailing list mention parasites that look like 鈥渓int鈥?and 鈥渉airs鈥? (Posts byJules and Curtis W. King.)1999, Oct - Posting on 鈥淓lliot鈥檚 Disease鈥? mentions involvement with the NPA.2000, Feb - NPA has a 鈥淩eporting Registry鈥?for Elliot鈥檚 Disease (or: 鈥渦ndetermined pathogens which may mimic lice and scabies鈥?, listing the following symptoms:
Sores or lesions, Biting or stinging sensation, Itching, Lumps on head/scalp, Sticky residue on skin, Sparkly particles on skin, Scaling skin, Hair breaking off, White specks on skin, Black specks on skin, Problem in genital area, Itchy, watery eyes, Crawling sensation, Rash, Tracking marks on skin, Hard/crusty shell-like particles on skin, Fibers/lint/fuzzy artifacts, Hair-like dust particles, Symptoms worse at night, Tiny salt-like crystals on skin, Skin discoloration, Scarring

TMAU.

A rare disease is a disease that hits your as*s only once but yet for the last time in your life

rare skin shedding disease:
http://www.10news.com/health/3919722/det...

and another rare disease, called "Dandy-Walker Syndrome"
http://www.ninds.nih.gov/disorders/dandy...

but which isn't as cheerful as it sounds

Hutchinson-Gilford Progeria Syndrome (HGPS)is a disease that accelerates aging in about one in eight million children. 6 and 10 year olds look like they're in their eighties. The disease is lethal and few afflicted teens ever get beyond 20.

There are thousands of rare diseases.
Try this site:
http://www.hon.ch/HONselect/RareDiseases...
It has a good list of rare diseases and each disease has a link that you can click on with links to tons of websites with detailed information about each disease.

Systemic Mastocytosis. oh, and by the way, House is so phony baloney. Some of the facts fit, but the diseases/poisonings profiled on the show do not tend to present in the matter they are portrayed.

I actually knew someone who had this. It is very rare. It involves a proliferation and dysfunction of mast cells, which typically release histamine in event of allergic reaction.

In Systemic mastocytosis, the mast cells proliferate on various organs such as skin, digestive, respiratory, brain, etc. Their numbers are many, and their cell membranes are very unstable and thus can suddenly release deadly amounts of histamine. This can appear as anaphylactic shock... like a severe allergic reaction to a food or insect sting. A dose of epinepherine can save the person. The weird thing, is that there is not necessarily any allergy trigger or response. My friend tested negative on skin prick and RAST to IgE mediated allergies. It was soley the random release of histamine out of the diseased mast cells that would cause her reactions, with typical anaphylactic response, such as drop of blood pressure, skin rash, breathing difficulty, etc.

People with systemic mastocytosis can require increasing doses of adrenaline, such that a safe dose no longer works. They can and do eventually die from an anaphylatic response.

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