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Is there a link between the drug macrodantin and Pulmonary Fibrosis?


My 80 year old mother was just diagnosed with Pulmonary Fibrosis. We're learning about it now. She's had increased shortness of breath over the months and has a dry cough for quite some time. Many years ago (probably 5-8...she can't remember), she took the drug Macrodantin to help relieve her urinary track infections. I'm just understanding now there could be a link between that and developing pulmonary fibrosis. Can anyone comment and/or offer some insight? Her condition is considered "moderate" by a pulmanologist. She's about to undergo the "breathing functionality" test, but hasn't done so as of yet. I would appreciate any feedback. Thanks in advance. Also should she be changing her diet at all (or any tips there?). Thanks.

Macrodantin

Respiratory:
CHRONIC, SUBACUTE, OR ACUTE PULMONARY HYPERSENSITIVITY REACTIONS MAY OCCUR.

CHRONIC PULMONARY REACTIONS OCCUR GENERALLY IN PATIENTS WHO HAVE RECEIVED CONTINUOUS TREATMENT FOR SIX MONTHS OR LONGER. MALAISE, DYSPNEA ON EXERTION, COUGH, AND ALTERED PULMONARY FUNCTION ARE COMMON MANIFESTATIONS WHICH CAN OCCUR INSIDIOUSLY. RADIOLOGIC AND HISTOLOGIC FINDINGS OF DIFFUSE INTERSTITIAL PNEUMONITIS OR FIBROSIS, OR BOTH, ARE ALSO COMMON MANIFESTATIONS OF THE CHRONIC PULMONARY REACTION. FEVER IS RARELY PROMINENT.

THE SEVERITY OF CHRONIC PULMONARY REACTIONS AND THEIR DEGREE OF RESOLUTION APPEAR TO BE RELATED TO THE DURATION OF THERAPY AFTER THE FIRST CLINICAL SIGNS APPEAR. PULMONARY FUNCTION MAY BE IMPAIRED PERMANENTLY, EVEN AFTER CESSATION OF THERAPY. THE RISK IS GREATER WHEN CHRONIC PULMONARY REACTIONS ARE NOT RECOGNIZED EARLY.

Dietary changes can be very effective in reducing inflammation which is seen in pulmonary fibrosis. I do not know what changes your Mom can make because I do not know her current diet, however, check out Dr. Andrew Weil in a search engin. Blessings. Report It

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