Are these disorders fatal?

Phenylketonuria(PKU)
Duchenne Muscular Dystrophy
Hemophilia
Down Syndrome

Phenylketonuria is a blood deficiency--usually treated by diatary measures (no meats or protein foods) it is NOT fatal if treated and a strict diet adhered to...

Duchenne Muscular Dystrophy is well known thanks to the Jerry Lewis telethons every September.... it is NOT necessarily fatal, however complications often arrise that often do cause premature death... As we KNOW from watching the telethons every year, people who are stricken wtth muscular dystrophy CAN live long lives but rarely do...

Hemophilia is a blood disorder where even the slightest scratch can cause one to bleed to death... patients are usually in need of many blood transfusions throughout their lives... the most notible hemophiliac was a boy named RYAN WHITE who contracted aids and died from the AIDS VIRUS from tainted blood he received in the hospital to combat his hemophilia... to learn more about it---look up RYAN WHITE on Yahoo search or google...

DownsSyndrome CAN be fatal and most people do NOT live to a ripe old age... but usually death is attributed to something related to the Dwns Syndrome but not necessarily the syndrome itself.... much like Duchenne Muscular Dystrophy in that aspect... Downs Syndrome kids are just about the kindest and most loving children you might EVER encounter... they LOOK different and speak differently as their tongues are usually oversized which makes their speech sound rather slurred... but they can be EXTREMELY intelligent, even to the point of going to college and doing well.... but unfortunately, society still looks upon them as being slow and holds them back.... To learn more about Downs Syndrome and how far afflicted people CAN go in life... check out CHRIS BURKE----he is a Downs Syndrome man who is an actor and held his own on a TV show many years ago as the shows STAR...

So, each one of your chosen maladies is not fatal unto itself.. but CAN be fatal or bring about other fatal illnesses ....in each, however, the life span is presumed to be considerably less then the average life span...

the first 3 could be, but Down Syndrome is not fatal.

--Down Syndrome: Yes, sort of. Their life expectancy is much lower than those without the disease...probably around 40 years old (though of course there are exceptions.)
--Homophilia: Yes, in a way. Some people don't know they have this disease, and if they go into surgery or something, they may bleed to death. But acquired hemophilia is pretty fatal--its when you randomly bleed for no reason into the soft tissue and skin. Acquired hemophilia is fatal in 22% of patients.
--Muscular Dystrophy: Yes. The life expectancy is about 25 years old.
--PKU: If it is not treated, then yes, probably. It can be controlled by diet. If untreated--or not properly treated--then it can lead to progressive mental retardation and seizures