Researching the use of beta-glucans / polysaccharides which have been shown to be effective against allogenic tumors. Not sure what type of tumors are caused by Ovarian Cancer cells. I believe you have some of your terms confused. "Allogeneic" refers to receiving a body part (marrow, heart, liver, etc.) from someone else as in the form of a transplant. "Syngeneic" refers to receiving a transplanted organ from an identical sibling. "Synergistic" refers to multiple items having a greater than additive effect (i.e. 1+1 = 3) on something.
A lot of research into cancer vaccines have been fueled by the identification of unique proteins/polysaccharides on the surface of cancer cells. However, it must be remembered, that the cancers that develop in someone, ovarian or otherwise, contain the same DNA that all of your other cells contain. Therefore, all of the cells in your body are capable of producing these "unique" substances. However, cancers proliferate by altering the expression of certain DNA sequences that the other cells do not.
Ovarian cancer cells, and all cancer cells, produce tumors that cannot be described as "allogeneic" since they were not transplanted into the patient. Laboratory research does involve the implantation of cancer cells into animals, for example. These tumors would be described as "xenogeneic" since they were derived from a different species. I agree with the above answer. It was an excellent question. |
