mcrh.org
*Home>>>Obesity

How obesity leads to diabetes?


How obesity leads to diabetes?
what are the scientific theory behind it?

The type of diabetes which is connected with obesity is called Type 2. It is characterized by a change in the way most (about 2/3) of the body cells respond to insulin. Usually, insulin causes cells to take in glucose from the blood. Type 2 diabetics don't do this -- some more than others. The tendency toward this change is clearly inherited and strongly so. Parents or other relatives with Type 2 consderably increase one's chances of getting it.

Yet, even with such ancestors, one will not always develop Type 2 diabetes. There is, in many (most? all?) cases, a trigger. Obesity seems to be one of these.

Only recently have we learned that fat tissue, to the considerable surpise of most everyone, is very active chemically. It is not merely a passive storage system against future need. And fat tissue near the abdominal organs (called visceral fat) is specially active. So active that it's host to a kind of inflammation (think agitated immune system cells). Fat just under the skin, or in thighs and such, is rather less of an issue. Among the signalling chemicals fat releases (there are probably more than we know, but we haven't been looking for very long) is one which indeed reduces cells' response to insulin. It's even been given the name 'resistin' (from resist, ie, insulin). There are likely more, and we don't understand any of this in much detail.

It appears that this is the reason weight loss will often help Type 2's in clincal situations. Whatever the research lab situation is, we all live in the real world. Even a small reduction in that abdominal fat seems to have considerable benefit, so there's probably some sort of trigger mechanism (beyond this amount of abdominal fat, the inflammation gets going and ...) but just how and what is obscure for now.

i have heard that it contributes to it i am not sure how though.

From my readings, both diabetes and obesity can result from the same cause, high insulin production.

For basic information on hyperinsulinemia (high insulin), check out www.hufa.org.

need to consult a doctor

Too much sugar in your diet.

Fat cells block insulin from getting to the blood.

Pegasus90 is right, through increased secretion of insulin by pancreas.

here is a website for you: http://www.mercola.com/2004/nov/3/obesit...

just type in a fake email address to read the article.

It usually begins as insulin resistance, a disorder in which the cells do not use insulin properly. As the need for insulin rises, the pancreas gradually loses its ability to produce it. Type 2 diabetes is associated with older age, obesity, family history of diabetes, history of gestational diabetes, impaired glucose metabolism, physical inactivity, and race/ethnicity

with increasing fat mass especially around the waist ,cells become more resistant to the action of insulin, a sugar lowering hormone.to reduce the sugar levels the insulin producing pancreas works harder and harder until a time when it exhausts.diabetes then develops.

The fat cells stop the insulin from getting thru the body. Thats all the better reason to exercise, to circulate the blood flow better.

i think they correlate with each other. (and not one affects the other)

a diet high in sugar will lead to both obesity and diabetes.

Obesity is associated with metabolic syndrome, where the insulin in one's body becomes less effective in controlling the sugar levels. This is insulin resistance.

As the weight problem continues and it remains unchecked, an abnormal amount of sugar is flowing through the body that is not properly controlled and leads to various vascular problems, digestive problems and nerve damage.

Losing as much as 10% of one's body weight is said to significantly reduce this metabolic syndrome and even reduce the need for diabetic treatments for those already diagnosed.

Overweight diabetics are usually given drugs that aid their livers in metabolizing glucose effectively. It does not add nor subtract from the insulin flowing in the body, but when the liver can handle the glucose better, there is less sugar to create havoc. This may also release the insulin resistance factor that many overweight people have once diagnosed as diabetic.

The medication is just one part of the program. The other part is diet and exercise, which together, all three may lead to better glucose control and/or reduction in the impact of diabetes.

Lots of info here.

When u eat all that sugar and rice all of the fast food all that does is turn into starch that is what causes ur blood sugar to go up

Tags
  Omega-3 Fatty Acids   Ombudsman Programs   Occupational Therapy   Occupational Injuries   Occupational Health   Obsessive-Compulsive Disorder   Obesity   Nystagmus   Nut Allergy   Nursing Homes   Nuclear Scans   Nose Disorders
Related information
  • Is obesity a medical condition?

    Yes it is. I'm currently writing a thesis on Adult Obesity myself. Obesity is a medical condition that affects not only the US but also a large percentage of the world. Furthermore it is an Am...

  • Child obesity and unhealthy food advertising?

    Many people choose to blame the media for childhood obesity but liek anythign else, it IS primarily the parent's responsibility to 'shelter' and protect their children from harmful f...

  • Is obesity an early symptom of type II diabetes?

    The cause of type 2 diabetes or insulin resistance is not known. Right now it's all theories. It's not clear whether obesity causes insulin resistance or insulin resistance causes obesity...

  • Is obesity really a big problem?

    The obesity problem is a BIG problem (no pun intended). NOt only in adults but also in children of all ages. I want to become a pediatrician so that I can help save the next generations of children...

  • Is Obesity a choice?

    Obesity is usually the result of a sedentary life and overeating. It's not a disease, per se, but it can lead to some major diseases such as diabetes or heart trouble. It is a risk factor jus...

  • Is obesity an eating disorder?

    I think what you would be after would be compulsive eating, as eating disorders go. That might or might not result in obesity, but it could just as easily be controlled by bulemia. Obesity is the...

  • Is obesity really genetic?

    It's not a lie. There are genetic factors to obesity. A recent study found people with a certain gene have a 70% greater chance of being obese. Of course, this study found they averaged 3 k...

  • Where can I find info on obesity?

    google American obesity Org www.obesity.org ...

  •  

    Categories--Copyright/IP Policy--Contact Webmaster