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At what age do symptoms of neurofibromatosis start to appear?


I have a friend who thinks that he has this disease and he would like to know when symptoms start to appear. Please answer for both neurofibromatosis type 1 and type 2.

From infancy to 16 years of age.
Neurofibromatosis (NF) is a condition that causes tumors to grow on nerve tissue, producing skin and bone abnormalities. NF is often diagnosed in childhood, occasionally in infancy but usually around 3-16 years of age. The effects of the disease vary widely. Some children might live almost unaffected by the condition. Although rare, others might be severely disabled.

The second type, NF2, is known as bilateral acoustic neurofibromatosis and is rarer, seen in one in 50,000 births. People with NF2 usually develop tumors on the nerves in their ears, causing hearing loss, eventual deafness, and problems with balance.

In both types of neurofibromatosis, the severity of the disorder varies greatly. In families where more than one person has NF, the disorder can progress with different physical signs and complications for each person. When NF is first diagnosed in a child, it isn't possible to know right away if the child will have a mild form of the disease or will develop severe complications.

NF 1 can often be diagnosed in infancy or early childhood - there are skin changes - brown spots and freckles under the arms. In adolescence bumps and growths on the skin begin to appear. NF2 shows up as growths on the nerves to the inner ears and is usually not apparent until early adulthood.

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