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Why is there an increase in blood pressure if you have acute glomerulon nephritis?


please give me a pathophysiology of acute glomerulon nephritis preferably a diagram. thanks a lot

Pathophysiology: Glomerular lesions in acute glomerulonephritis are the result of glomerular deposition or in situ formation of immune complexes. On gross appearance, the kidneys may be enlarged up to 50%. Histopathologic changes include swelling of the glomerular tufts and infiltration with polymorphonucleocyte. Immunofluorescence reveals deposition of immunoglobulins and complement.

With the exception of poststreptococcal glomerulonephritis, the exact triggers for the formation of the immune complexes are unclear. In streptococcal infection, involvement of derivatives of streptococcal proteins has been reported. A streptococcal neuramidase may alter host immunoglobulin G (IgG). IgG combines with host antibodies. IgG/anti-IgG immune complexes are formed and then collect in the glomeruli. In addition, elevations of antibody titers to other antigens, such as antistreptolysin O or antihyaluronidase, DNAase-B, and streptokinase, provide evidence of a recent streptococcal infection.

Its a side effect of the medications which treat the disease.

Try these links...did a paper on it in school. Found some good stuff here.
http://www.healthsystem.virginia.edu/uva...
http://www.mayoclinic.com/health/glomeru...

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