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About infectious mononucleosis...?


I have recently had contact with a person who had infectious mononucleosis. He recovered 2 months ago. Is there any possibility that even though it had passed for him that now, 2 moths later, i have caught the virus?

no
Infectious mononucleosis
From Wikipedia, the free encyclopedia
(Redirected from Mononucleosis)
Jump to: navigation, search
Infectious mononucleosis ICD-10 B27
ICD-9 075
Infectious mononucleosis (also known in North America as mono, the kissing disease or Pfeiffer's disease, and more commonly known as glandular fever in other English-speaking countries) is a disease seen most commonly in adolescents and young adults, characterized by fever, sore throat and fatigue. It is caused by the Epstein-Barr virus (EBV) or the cytomegalovirus (CMV). It is typically transmitted from asymptomatic individuals through saliva or blood, or by sharing a drinking glass, eating utensils, or needles. The disease is far less contagious than is commonly thought. Since the causative virus is also found in the mucus of the infected person, it can also spread through coughing or sneezing.

It is estimated that 90% to 95% of adults in the world have EBV-antibodies, having been infected with the Epstein-Barr virus at some point in their lives. The vast majority of infections do not result in the development of mononucleosis. The virus infects B cells (B-lymphocytes), producing a reactive lymphocytosis and the atypical T cells (T-lymphocytes). Early childhood infections often cause no symptoms. In developed countries with less crowded conditions and better hygiene, children do not commonly become infected until adolescence. Since they also typically begin dating at that age, the co-occurrence of mono and kissing have led to its being called the "kissing disease," although this is but one of its modes of transmission.

The disease is so-named because the count of mononuclear leukocytes (white blood cells with a one-lobed nucleus) rises significantly. There are two main types of mononuclear leukocytes: monocytes and lymphocytes. They normally account for about 35% of all white blood cells. With Mono, it can become 50-70% Also, the total white blood count increases 10000-20000 per cubic millimeter.

Contents [hide]
1 Epidemiology
2 Clinical presentation
3 Atypical presentations of mononucleosis/EBV infection
4 Laboratory tests
5 Treatment
6 Mortality/morbidity
6.1 Interactions with common drugs
7 External links



[edit]
Epidemiology
The incidence of clinically recognizable infectious mononucleosis caused by EBV is estimated at 45 per 100 000 in the US. In developing countries, an estimated 90% of children undergo an asymptomatic EBV-infection, and thus are not susceptible to infectious mononucleosis of EBV.

[edit]
Clinical presentation
A person can be infected with the virus for weeks or months before any symptoms appear. Symptoms usually appear 4-7 weeks after infection, and may resemble strep throat or other bacterial or viral respiratory infections. These first signs of the disease are commonly confused with cold and flu symptoms. The typical symptoms and signs of mononucleosis are:

Fever - this varies from mild to severe, but is seen in nearly all cases.
Enlarged and tender lymph nodes - particularly the posterior cervical lymph nodes, on both sides of the neck.
Sore throat - seen in nearly all patients with EBV-mononucleosis
Fatigue (sometimes extreme fatigue)
Some patients also display:

Enlarged spleen (splenomegaly, which may lead to rupture) or liver (hepatomegaly)
Abdominal pain
Aching muscles
Headache
Loss of appetite
Jaundice
Depression
Weakness
Skin rash
After an initial prodrome of 1-2 weeks, the fatigue of mono often lasts from 1-2 months. The virus can remain dormant in the B cells indefinitely after symptoms have disappeared, and resurface at a later date. Many people exposed to the Epstein-Barr virus do not show symptoms of the disease, but carry the virus and can transmit it to others. This is especially true in children, in whom infection seldom causes more than a very mild illness which often goes undiagnosed. This feature, along with mono's long incubation period, makes epidemiological control of the disease impractical. About 6% of people who have had mono will relapse.

Mononucleosis can cause the spleen to swell, which in rare cases may lead to a ruptured spleen. Rupture may occur without trauma, but impact to the spleen is usually a factor. Other complications include hepatitis (inflammation of the liver) causing jaundice, and anemia (a deficiency of red blood cells). In rare cases, death may result from severe hepatitis or splenic rupture.

Reports of splenomegaly (enlarged spleen) in infectious mononucleosis suggest variable prevalence rates of 25% to 75%. Among pediatric patients, a splenomegaly rate of 50% is expected,[1] with a rate of 60% reported in one case series.[2] Although splenic rupture is a rare complication of infectious mononucleosis, it is the basis of advice to avoid contact sports for 4-6 weeks after diagnosis.

Usually, the longer the infected person experiences the symptoms the more the infection weakens the person's immune system and the longer he/she will need to recover. Cyclical reactivation of the virus, although rare in healthy people, is often a sign of immunological abnormalities in the small subset of organic disease patients in which the virus is active or reactivated.

Although the great majority of cases of mononucleosis are caused by the E.B. virus, cytomegalovirus can produce a similar illness, usually with less throat pain. Due to the presence of the atypical lymphocytes on the blood smear in both conditions, most clinicians include both infections under the diagnosis of "mononucleosis." Symptoms similar to those of mononucleosis can be caused by adenovirus and the protozoan Toxoplasma gondii.

[edit]
Atypical presentations of mononucleosis/EBV infection
In small children, the course of the disease is frequently asymptomatic. The course of the disease can also be chronic. Some patients suffer fever, tiredness, lassitude (abnormal fatigue), depression, lethargy, and chronic lymph node swelling, for months or years. This variant of mononucleosis is often referred to as chronic EBV syndrome or chronic fatigue syndrome. In case of a weakening of the immune system, a reactivation of the Epstein-Barr Virus is possible, though the course of the resultant disease is usually milder.

[edit]
Laboratory tests

Atypical lymphocyteThe laboratory hallmark of the disease is the presence of so-called atypical lymphocytes (a type of mononuclear cell, see image) on the peripheral blood smear. In addition, the overall white blood cell count is almost invariably increased, particularly the number of lymphocytes.

The mono spot tests for infectious mononucleosis by examining the patient's blood for so-called heterophile antibodies, which cause agglutination (sticking together) of non-human red blood cells. This screening test is non-specific. Confirmation of the exact etiology can be obtained through tests to detect antibodies to the causative viruses. The mono spot test may be negative in the first week, so negative tests are often repeated at a later date. Since the mono spot test is usually negative in children less than 6-8 years old, an EBV serology test should be done on them if mononucleosis is suspected.

An older test is the Paul Bunnell test, in which the patient's serum is mixed with sheep red blood cells. If EBV is present, antibodies will usually be present that cause the sheep's blood cells to agglutinate. This test has been replaced by the mono spot and more specific EBV and CMV antibody tests.

[edit]
Treatment
Because mononucleosis is a viral infection, antibiotics are not effective, but a January 2006 study conducted at the University of Minnesota demonstrated that 3 grams a day of the antiviral Valtrex (acyclovir or valacyclovir) for two weeks (or longer) is effective in treating mono ([1]). Another antiviral, valganciclovir (Valcyte) which has a longer intracellular half-life, may be even more effective than Valtrex. Most doctors recommend generous amounts of bed rest, drinking a lot of fluids, and avoiding caffeine. Trying to be active to beat the fatigue may make it worse. The duration of symptoms may vary from weeks to months, with some cases lasting from six months to a year. Even after the initial symptoms are gone, there may still be a risk of rupturing the spleen. Athletes involved in contact sports should receive medical clearance before resuming full activity.

[edit]
Mortality/morbidity
Fatalities from mononucleosis are very rare in developed nations. Potential mortal complications include splenic rupture, bacterial superinfections, hepatic failure and the development of viral myocarditis.
Uncommon, nonfatal complications are rarely seen, but include various forms of CNS and hematological affection.
CNS: Meningitis, encephalitis, hemiplegia, Guillain-Barre syndrome and transverse myelitis. EBV infection has also been proposed as a risk factor for the development of multiple sclerosis (MS), but this has not been affirmed.
Hematologic: EBV can cause autoimmune hemolytic anemia (direct Coombs test is positive) and various cytopenias.
[edit]
Interactions with common drugs
Aspirin should be avoided, since its use in patients with mononucleosis can cause Reye's syndrome.
Paracetamol (acetaminophen) should be used with caution, as it may worsen the hepatitis that often accompanies mononucleosis.
Ampicillin and amoxicillin should also be avoided, since they cause an allergic-like rash in 90% of mono patients. This rash may then be incorrectly diagnosed as an allergic reaction to penicillin.
In cases accompanied by severe throat pain, corticosteroids may be judiciously prescribed, although some studies have shown that such treatment may increase the risk of the EBV causing lymphomas in later years.

No, you'd be sick by now. Your body may have had enough to fight it off altogether. I got it down in Mexico from unwashed vegetables handled by a person with mono and I was sick within a month.

You can always get a blood test to find out for sure, but if you had mono, you would know. You would be falling asleep as you wrote your question!!

No.

Infectious mononucleosis
From Wikipedia, the free encyclopedia
Jump to: navigation, search
Infectious mononucleosis ICD-10 B27
ICD-9 075
Infectious mononucleosis (also known in North America as mono, the kissing disease or Pfeiffer's disease, and more commonly known as glandular fever in other English-speaking countries) is a disease seen most commonly in adolescents and young adults, characterized by fever, sore throat and fatigue. It is caused by the Epstein-Barr virus (EBV) or the cytomegalovirus (CMV). It is typically transmitted from asymptomatic individuals through saliva or blood, or by sharing a drinking glass, eating utensils, or needles. The disease is far less contagious than is commonly thought. Since the causative virus is also found in the mucus of the infected person, it can also spread through coughing or sneezing.

It is estimated that 90% to 95% of adults in the world have EBV-antibodies, having been infected with the Epstein-Barr virus at some point in their lives. The vast majority of infections do not result in the development of mononucleosis. The virus infects B cells (B-lymphocytes), producing a reactive lymphocytosis and the atypical T cells (T-lymphocytes). Early childhood infections often cause no symptoms. In developed countries with less crowded conditions and better hygiene, children do not commonly become infected until adolescence. Since they also typically begin dating at that age, the co-occurrence of mono and kissing have led to its being called the "kissing disease," although this is but one of its modes of transmission.

The disease is so-named because the count of mononuclear leukocytes (white blood cells with a one-lobed nucleus) rises significantly. There are two main types of mononuclear leukocytes: monocytes and lymphocytes. They normally account for about 35% of all white blood cells. With Mono, it can become 50-70% Also, the total white blood count increases 10000-20000 per cubic millimeter.

Contents [hide]
1 Epidemiology
2 Clinical presentation
3 Atypical presentations of mononucleosis/EBV infection
4 Laboratory tests
5 Treatment
6 Mortality/morbidity
6.1 Interactions with common drugs
7 External links



[edit]
Epidemiology
The incidence of clinically recognizable infectious mononucleosis caused by EBV is estimated at 45 per 100 000 in the US. In developing countries, an estimated 90% of children undergo an asymptomatic EBV-infection, and thus are not susceptible to infectious mononucleosis of EBV.

[edit]
Clinical presentation
A person can be infected with the virus for weeks or months before any symptoms appear. Symptoms usually appear 4-7 weeks after infection, and may resemble strep throat or other bacterial or viral respiratory infections. These first signs of the disease are commonly confused with cold and flu symptoms. The typical symptoms and signs of mononucleosis are:

Fever - this varies from mild to severe, but is seen in nearly all cases.
Enlarged and tender lymph nodes - particularly the posterior cervical lymph nodes, on both sides of the neck.
Sore throat - seen in nearly all patients with EBV-mononucleosis
Fatigue (sometimes extreme fatigue)
Some patients also display:

Enlarged spleen (splenomegaly, which may lead to rupture) or liver (hepatomegaly)
Abdominal pain
Aching muscles
Headache
Loss of appetite
Jaundice
Depression
Weakness
Skin rash
After an initial prodrome of 1-2 weeks, the fatigue of mono often lasts from 1-2 months. The virus can remain dormant in the B cells indefinitely after symptoms have disappeared, and resurface at a later date. Many people exposed to the Epstein-Barr virus do not show symptoms of the disease, but carry the virus and can transmit it to others. This is especially true in children, in whom infection seldom causes more than a very mild illness which often goes undiagnosed. This feature, along with mono's long incubation period, makes epidemiological control of the disease impractical. About 6% of people who have had mono will relapse.

Mononucleosis can cause the spleen to swell, which in rare cases may lead to a ruptured spleen. Rupture may occur without trauma, but impact to the spleen is usually a factor. Other complications include hepatitis (inflammation of the liver) causing jaundice, and anemia (a deficiency of red blood cells). In rare cases, death may result from severe hepatitis or splenic rupture.

Reports of splenomegaly (enlarged spleen) in infectious mononucleosis suggest variable prevalence rates of 25% to 75%. Among pediatric patients, a splenomegaly rate of 50% is expected,[1] with a rate of 60% reported in one case series.[2] Although splenic rupture is a rare complication of infectious mononucleosis, it is the basis of advice to avoid contact sports for 4-6 weeks after diagnosis.

Usually, the longer the infected person experiences the symptoms the more the infection weakens the person's immune system and the longer he/she will need to recover. Cyclical reactivation of the virus, although rare in healthy people, is often a sign of immunological abnormalities in the small subset of organic disease patients in which the virus is active or reactivated.

Although the great majority of cases of mononucleosis are caused by the E.B. virus, cytomegalovirus can produce a similar illness, usually with less throat pain. Due to the presence of the atypical lymphocytes on the blood smear in both conditions, most clinicians include both infections under the diagnosis of "mononucleosis." Symptoms similar to those of mononucleosis can be caused by adenovirus and the protozoan Toxoplasma gondii.

[edit]
Atypical presentations of mononucleosis/EBV infection
In small children, the course of the disease is frequently asymptomatic. The course of the disease can also be chronic. Some patients suffer fever, tiredness, lassitude (abnormal fatigue), depression, lethargy, and chronic lymph node swelling, for months or years. This variant of mononucleosis is often referred to as chronic EBV syndrome or chronic fatigue syndrome. In case of a weakening of the immune system, a reactivation of the Epstein-Barr Virus is possible, though the course of the resultant disease is usually milder.

[edit]
Laboratory tests

Atypical lymphocyteThe laboratory hallmark of the disease is the presence of so-called atypical lymphocytes (a type of mononuclear cell, see image) on the peripheral blood smear. In addition, the overall white blood cell count is almost invariably increased, particularly the number of lymphocytes.

The mono spot tests for infectious mononucleosis by examining the patient's blood for so-called heterophile antibodies, which cause agglutination (sticking together) of non-human red blood cells. This screening test is non-specific. Confirmation of the exact etiology can be obtained through tests to detect antibodies to the causative viruses. The mono spot test may be negative in the first week, so negative tests are often repeated at a later date. Since the mono spot test is usually negative in children less than 6-8 years old, an EBV serology test should be done on them if mononucleosis is suspected.

An older test is the Paul Bunnell test, in which the patient's serum is mixed with sheep red blood cells. If EBV is present, antibodies will usually be present that cause the sheep's blood cells to agglutinate. This test has been replaced by the mono spot and more specific EBV and CMV antibody tests.

[edit]
Treatment
Because mononucleosis is a viral infection, antibiotics are not effective, but a January 2006 study conducted at the University of Minnesota demonstrated that 3 grams a day of the antiviral Valtrex (acyclovir or valacyclovir) for two weeks (or longer) is effective in treating mono ([1]). Another antiviral, valganciclovir (Valcyte) which has a longer intracellular half-life, may be even more effective than Valtrex. Most doctors recommend generous amounts of bed rest, drinking a lot of fluids, and avoiding caffeine. Trying to be active to beat the fatigue may make it worse. The duration of symptoms may vary from weeks to months, with some cases lasting from six months to a year. Even after the initial symptoms are gone, there may still be a risk of rupturing the spleen. Athletes involved in contact sports should receive medical clearance before resuming full activity.

[edit]
Mortality/morbidity
Fatalities from mononucleosis are very rare in developed nations. Potential mortal complications include splenic rupture, bacterial superinfections, hepatic failure and the development of viral myocarditis.
Uncommon, nonfatal complications are rarely seen, but include various forms of CNS and hematological affection.
CNS: Meningitis, encephalitis, hemiplegia, Guillain-Barre syndrome and transverse myelitis. EBV infection has also been proposed as a risk factor for the development of multiple sclerosis (MS), but this has not been affirmed.
Hematologic: EBV can cause autoimmune hemolytic anemia (direct Coombs test is positive) and various cytopenias.
[edit]
Interactions with common drugs
Aspirin should be avoided, since its use in patients with mononucleosis can cause Reye's syndrome.
Paracetamol (acetaminophen) should be used with caution, as it may worsen the hepatitis that often accompanies mononucleosis.
Ampicillin and amoxicillin should also be avoided, since they cause an allergic-like rash in 90% of mono patients. This rash may then be incorrectly diagnosed as an allergic reaction to penicillin.
In cases accompanied by severe throat pain, corticosteroids may be judiciously prescribed, although some studies have shown that such treatment may increase the risk of the EBV causing lymphomas in later years. What is infectious mononucleosis?

Infectious mononucleosis is a viral disease that affects certain blood cells. It is caused by the Epstein-Barr virus (EBV), which is a member of the herpes virus family. Most cases occur sporadically. Outbreaks are rare.

Who gets infectious mononucleosis?

While most people are exposed to the Epstein-Barr virus sometime in their lives, very few go on to develop the symptoms of infectious mononucleosis. In underdeveloped countries, people are exposed in early childhood where they are unlikely to develop noticeable symptoms. In developed countries such as the United States, the age of first exposure may be delayed to older childhood and young adult age when symptoms are more likely to result. For this reason, it is recognized more often in high school and college students.

How is infectious mononucleosis spread?

The virus is spread by person to person contact, via saliva (on hands or toys, or by kissing). In rare instances, the virus has been transmitted by blood transfusion.

What are the symptoms of infectious mononucleosis?

Symptoms include fever, sore throat, swollen glands and feeling tired. Sometimes, the liver and spleen are affected. Duration is from one to several weeks. The disease is very rarely fatal.

How soon do symptoms appear?

Symptoms appear from four to six weeks after exposure.

When and for how long is a person able to spread infectious mononucleosis?

The virus is shed in the throat during the illness and for up to a year after infection. After the initial infection, the virus tends to become dormant for a prolonged period and can later reactivate and be shed from the throat again.

What is the treatment for infectious mononucleosis?

No treatment other than rest is needed in the vast majority of cases.

What can a person do to minimize the spread of infectious mononucleosis?

Avoid activities involving the transfer of body fluids (commonly saliva) with someone who is currently or recently infected with the disease. At present, there is no vaccine available to prevent infectious mononucleosis.


Definition

Infectious mononucleosis is a contagious illness caused by the Epstein-Barr virus that can affect the liver, lymph nodes, and oral cavity. While mononucleosis is not usually a serious disease, its primary symptoms of fatigue and lack of energy can linger for several months.

Description

Infectious mononucleosis, frequently called "mono" or the "kissing disease," is caused by the Epstein-Barr virus (EBV) found in saliva and mucus. The virus affects a type of white blood cell called the B lymphocyte producing characteristic atypical lymphocytes that may be useful in the diagnosis of the disease.

While anyone, even young children, can develop mononucleosis, it occurs most often in young adults between the ages of 15 and 35 and is especially common in teenagers. The mononucleosis infection rate among college students who have not previously been exposed to EBV has been estimated to be about 15%. In younger children, the illness may not be recognized.

The disease typically runs its course in four to six weeks in people with normally functioning immune systems. People with weakened or suppressed immune systems, such as AIDS patients or those who have had organ transplants, are particularly vulnerable to the potentially serious complications of infectious mononucleosis.

Causes and symptoms

The EBV that causes mononucleosis is related to a group of herpes viruses, including those that cause cold sores, chicken pox, and shingles. Most people are exposed to EBV at some point during their lives. Mononucleosis is most commonly spread by contact with virus-infected saliva through coughing, sneezing, kissing, or sharing drinking glasses or eating utensils.

In addition to general weakness and fatigue, symptoms of mononucleosis may include any or all of the following:


Sore throat and/or swollen tonsils


Fever and chills


Nausea and vomiting, or decreased appetite


Swollen lymph nodes in the neck and armpits


Headaches or joint pain


Enlarged spleen


Jaundice


Skin rash.

Complications that can occur with mononucleosis include a temporarily enlarged spleen or inflamed liver. In rare instances, the spleen may rupture, producing sharp pain on the left side of the abdomen, a symptom that warrants immediate medical attention. Additional symptoms of a ruptured spleen include light headedness, rapidly beating heart, and difficulty breathing. Other rare, but potentially life-threatening, complications may involve the heart or brain. The infection may also cause significant destruction of the body's red blood cells or platelets.

Symptoms do not usually appear until four to seven weeks after exposure to EBV. An infected person can be contagious during this incubation time period and for as many as five months after the disappearance of symptoms. Also, the virus will be excreted in the saliva intermittently for the rest of their lives, although the individual will experience no symptoms. Contrary to popular belief, the EBV is not highly contagious. As a result, individuals living in a household or college dormitory with someone who has mononucleosis have a very small risk of being infected unless they have direct contact with the person's saliva.

Diagnosis

If symptoms associated with a cold persist longer than two weeks, mononucleosis is a possibility; however, a variety of other conditions can produce similar symptoms. If mononucleosis is suspected, a physician will typically conduct a physical examination, including a "Monospot" antibody blood test that can indicate the presence of proteins or antibodies produced in response to infection with the EBV. These antibodies may not be detectable, however, until the second or third weeks of the illness. Occasionally, when this test is inconclusive, other blood tests may be conducted.

Treatment

The most effective treatment for infectious mononucleosis is rest and a gradual return to regular activities. Individuals with mild cases may not require bed rest but should limit their activities. Any strenuous activity, athletic endeavors, or heavy lifting should be avoided until the symptoms completely subside, since excessive activity may cause the spleen to rupture.

The sore throat and dehydration that usually accompany mononucleosis may be relieved by drinking water and fruit juices. Gargling salt water or taking throat lozenges may also relieve discomfort. In addition, taking over-the-counter medications, such as acetaminophen or ibuprofen, may relieve symptoms, but aspirin should be avoided because mononucleosis has been associated with Reye's syndrome, a serious illness aggravated by aspirin.

While antibiotics do not affect EBV, the sore throat accompanying mononucleosis can be complicated by a streptococcal infection, which can be treated with antibiotics. Cortisone anti-inflammatory medications are also occasionally prescribed for the treatment of severely swollen tonsils or throat tissues.

Prognosis

While the severity and length of illness varies, most people diagnosed with mononucleosis will be able to return to their normal daily routines within two to three weeks, particularly if they rest during this time period. It may take two to three months before a person's usual energy levels return. One of the most common problems in treating mononucleosis, particularly in teenagers, is that people return to their usual activities too quickly and then experience a relapse of symptoms. Once the disease has completely run its course, the person cannot be re-infected.

Prevention

Although there is no way to avoid becoming infected with EBV, paying general attention to good hygiene and avoiding sharing beverage glasses or having close contact with people who have mononucleosis or cold symptoms can help prevent infection.

Key Terms


Antibody
A specific protein produced by the immune system in response to a specific foreign protein or particle called an antigen.


Herpes viruses
A group of viruses that can cause cold sores, shingles, chicken pox, and congenital abnormalities. The Epstein-Barr virus which causes mononucleosis belongs to this group of viruses.


Reye's syndrome
A very serious, rare disease, most common in children, which involves an upper respiratory tract infection followed by brain and liver damage.
For Your Information

Books



The Merck Manual. 16th ed. Whitehouse Station, NJ: Merck & Co., 1992.


Periodicals


Baily, Eugene R. "Diagnosis and Treatment of Infectious Mononucleosis." American Family Physician (Mar. 1994): 879-887.


Organizations


National Institute of Allergy and Infectious Disease. Building 31, Room 7A-50, 31 Center Drive MSC 2520, Bethesda, MD 20892-2520. (301) 496-5717. http://www.niaid.nih.gov/default.htm


Other


"Mononucleosis: A Tiresome Disease." Mayo Clinic Online. http://www.mayo.ivi.com/mayo/9701/htm/mo...


"Communicable Disease Fact Sheet." New York State Department of Health.

Typically IM runs its course in 10鈥?0 days.
The first symptoms of IM are usually general weakness and extreme fatigue. An infected person may require 12鈥?6 hours of sleep daily prior the development of other symptoms. IM symptoms are similar to cold or flu symptoms:
鈥?Fever and chills occurs in about 90% of IM cases. EBV is most contagious during this stage of the illness.
鈥?An enlarged spleen, causing pain in the upper left of the abdomen, occurs in about 50鈥?0% of infections.
鈥?Sore throat and/or swollen tonsils occurs in less than 50% of mononucleosis infections.
鈥?Swollen lymph glands (nodes) in the neck, armpits, and/or groin develop in less than 50% of infections.
鈥?Jaundice (yellowing of the skin and eyes) develops in more than 20% of patients, depending on age, and indicates an inflamed or enlarged liver.
鈥?A red skin rash, particularly on the chest, occurs in about 5% of infections.
鈥?loss of appetite
鈥?stomach pain and/or nausea
鈥?muscle soreness and/or joint pain
鈥?headache
鈥?chest pain
鈥?coughing
鈥?rapid or irregular heartbeat
These acute symptoms usually last one to two weeks.

yes, mono has a long span of time before it catches up with you. If he only had a positive mono test 2 months ago, chances are he was about over it by then. there isn't anything to do for it i don't think...but it is very contagious and a pain in the butt

It is possible; but not likely. Infectious Mono is a strange disease. Rarely does it infect more than one member of a family. And they live in close quarters.

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