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I need information about toxic epidermal necrolosys/steven johnson syndrome, and erythema multiforme.?


I have a friend who has been dignosed with;fibromyalga,chronic pain syndrome,DJD,osteoarthritis, angular chelitis,metabolic syndrome,depression,anxiety,and numerous other diagnosis. Is there any one out there who knows about "toxic epidermal necrolosys/steven johnson syndrome/erythema multiforme"?? If so is associated with any of these other diagnosis'?

Toxic epidermal necrolysis is a life-threatening skin disorder characterized by a blistering and peeling of the top layer of skin. This disorder can be caused by a drug reaction -- most often penicillin -- or another disease. About one-third of all diagnosed cases of toxic epidermal necrolysis are a result of unknown causes.

Toxic epidermal necrolysis can cause the skin to peel off in sheets, leaving large areas that look scalded. The loss of skin causes fluids and salts to ooze from the raw, damaged areas which can easily become infected. The following are the most common symptoms of toxic epidermal necrolysis. However, each person may experience symptoms differently:

a painful, red area that spreads quickly
the top layer of skin may peel without blistering
scalded-looking raw areas of flesh
discomfort
fever
condition spread to eyes, mouth, and genitals
The symptoms of toxic epidermal necrolysis may resemble other dermatologic conditions. Consult a physician for diagnosis.

The progression of the disease happens fast, usually within three days. Treatment usually includes hospitalization, often in the burn unit. If a medication is causing the skin reaction, the patient is immediately taken off the medication. Specific treatment for toxic epidermal necrolysis will be determined by your physician based on:

your overall health, age, and medical history
severity of the condition
your tolerance of specific medications, procedures, or therapies
your opinion or preference
Treatment may include one, or several, of the following:

isolation to prevent infection
protective bandages
intravenous fluid and electrolytes
antibiotics

Toxic epidermal necrolysis, Stevens Johnson syndrome, and erythema multiforme are all generally similar events but of different severity. Drugs can be one cause, so your friend who has multiple medical problems could be taking a drug that could cause this. One of the more common types of drugs that have been implicated are the sulphonamide drugs.

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