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Glomerulonephritis patient with 39.5degree fever...?


A 59 year old man with 14 year history of focal segmental glomerulosclerosis. U-albumin 2-5g/day at last checkup, GFR OK at last checkup. Hypercholesterolaemia. BMI 33 kg/m2. Smoker.

High dose Felodipin, metoprolol and irbesartan, but still high BP at regular checkups.

Recently (2 weeks ago) returned from holiday in Turkey
Vomited 3 days ago, since then no more vomit, but fever and general aches. Feels tired, worn out. Slight cough, some throat soreness.

Presents today for tiredness...

Fully conscious
Temp 39.5
Puls 136
BP 137/104
Lungs sound fine
Cardiac sounds faint, no murmurs
No flank pain, no other pain
Normal abdominal sounds


And that's all I've got!

I'm thinking possible ANF, possible sepsis with a hidden pressure drop (maybe he's normally over 200 - I don't know!), possibly a malignancy...

Any pointers gratefully received!

Have you considered intravenous bisphosphonates? Or a referral to a Kidney specialist?

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