Is cerebral Malaria curable?

One of my friends 3 year old son was affected with cerebral Malaria and Doctors are not giving a correct answer abt the Cure and if curable dos it come again?

HI, I copy - paste this articles for you, because it's way too long. Read them yourself ok ?

http://www.brown.edu/Courses/Bio_160/Pro...

As cerebral malaria is the fatal within days of malaria infection if left untreated, immediate treatment is crucial. Because natural immunity to malaria is not fully understood (Immunity) and thus cannot yet be artificially imitated by drugs, control and prevention strategies are significant. Two of these are antimalarial chemotherapy and adjunctive measures. Public health interventions are also critical

Chemotherapy for cerebral malaria now primarily involves the use of quinine, for a patient with severe CM must be assumed to have chloroquine resistance. It is one of the four main alkaloids found in the bark of the Cinchona tree and is the only drug which over a long period of time has remained largely effective for treating the disease. Quinine has similar activity to chloroquine in that it is likely to interfere with the parasite鈥檚 enzymatic digestion.

Artemisinins have been shown in some clinical trials to clear parasitemia and fever faster than quinine or chloroquine, but they had no effect on mortality rates. Artemisinin has been used by the Chinese as a traditional treatment for fever and malaria. It is a sesquiterpene lactone derived from Artemisia annua. The two most widely used are artesunate and artemether. Because it is both cheap and effective, it is beginning to be included in treatment schedules. However, it is not yet licensed for use in Australia, North America or Europe. Its main value is in the treatment of multi-drug resistant falciparum malaria. As the possibility of quinine resistance looms, artemisinin and its derivatives may soon become the drugs of choice for CM treatment (Newton and Warrell).
Adjunctive measures for CM treatment exist, but they are debatable in both use and efficacy:

Anti-pyretics
Such as paracetamol to reduce fever. However, it is not clear if a reduction in core temperature benefits cerebral consequences.

Anti-convulsants
Such as phenobarbital sodium for seizures. It is crucial to control or prevent seizures, as they can cause neuronal damage and are associated with a fatal outcome.

Reduce intracranial pressure
Using agents such as osmotic diuretics.

Hypoglycemia correction
Using hypertonic glucose. However, theoretically, correcting hypoclycemia in the presence of tissue hypoxia can worsen tissue acidosis.

Exchange transfusion
Generally only been justified when peripheral parasitemia exceeds 10% of circulating erythrocytes. The role of these blood transfusions remains highly controversial, as they are both expensive and potentially dangerous in many malaria-endemic areas.

Anti-Inflammatories
Such as corticosteroids. However, there have been few controlled studies demonstrating benefit.

Desferrioxamine
An iron-chelating adjuvant agent with antimalarial properties. Reduces formation of reactive oxygen species by reducing amount of free iron.

Microcirculatory Flow 颅
Such as pentoxifylline. Reduces red cell deformability and blood viscosity, decreases systemic vascular resistance, and impairs platelet aggregation, thus improving microcirculatory flow.

Hope this help.

YES! I know that Much... But More Info I cant give you sorry

Well think about this: <Cer-e'bal> is of the brain !! . It's main discription should leave those familiar with the human anatomy aware that it's a condition of the or to the brain !! Or if you break the word or words down.. It's talking about a certain part or condition of the brain !! such as something called:<cerebral palsy>!!... & or now Malaria is an infectious disease transmitted by the mosquito !?! or a certain kind or type of that insect !?! characterized by severe chills & fever. So it's possible !?! I guess that if there is a cure for it .. I guess it would've been talked about more in the media !?! Or maybe some medical journal !?! Or you'd see tV ads about a solution or cure !?! So it might be alot more of a problem than some may think!?!.. So when you might see a certain program that mostly last anywhere fom 24 hours to I guess a weekend !?! & you'll hear JERRY's Kids mentioned!!.. "Be a pal & donate a`little something !! It truly does go toward a GOOD cause !! RrRr...












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Yes, it is curable with antimalarial drugs like quinine, chloroquine and artemether. However, it may rarely lead to permanent brain or kidney damage. Recurrent infection is possible, if proper precautions against mosquito bites are not taken and preventive antomalarial drugs are not taken.

Cerebral malaria is caused by the Plasmodim Falciparum malaria spieces and is treatable using the correct treatment which is usually Quinine Intravenously, but now being used commonly in Africa now is Artemether-lumefantrine, commercial name Coartem. Cerebral malaria can lead to fatality if not treated correctly. Once adequately treated it does not return, unless its P. Vivax or P.Ovale, but these spieces do not cause cerebral malaria.