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I have a chronic liver disease with unusual lab and biopsy findings.?


Labs: Elevated AST and ALT. GGT is consistently above 500. AP, Bilirubin, PT, LDH are WNL. Hepatitis profile for B and C were wnl. (vaccinated against A in 2000). Sed Rate 40. All ANA tests normal. Cerulugen normal. CBC normal.

CT shows multiple large cysts consistent with Poly cystic Liver disease without renal involvement. CT showed same density in spleen and liver.

Biopsy showed occasional cellular edema with Mast Cells, Eosinophils, and some lymphocytes. No fibrosis. Mild patches of fat noted.

No history of drug or alcohol consumption. Non-smoker.

Maybe some medical student out there can figure this one out. Ask on of your professors. All the physicians I have seen have no idea other than say it may be combination of conditions.

additional details:

University based Hepatologist have already been consulted. They don't know either

Figure out what? You have liver disease which has multiorgan impact. What is it that you don't understand or want us to tell you? Bottom line, liver disease is a complex disease, so just work with you doctors on this. Except for entertainment it's not a discussion appropriate to YA. Hopefully you have a liver specialist on your team and not just a primary care MD. Good luck.

Chronic hepatocyte destruction because of cysts. Amenable to surgical decompression.

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