connected to Kidneys and low sodium Liver disease can be caused by many things besides alcohol. Medication, viral infections (like hepatitis C) and other reasons can cause liver disease. When the liver is compromised and not working well, it can cause extra-hepatic manifestations (extra= outside of , hepatic=liver). It is difficult to say with the limited information provided, but yes, it can be connected. Best wishes. most liver problems due to drinking alcohol...salt/sodium has bigger affect on kidney | 