Is it cureable, how do you find a compentent physician From wiki:
There are two common therapies containing antimony (known as pentavalent antimonials), meglumine antimoniate (Glucantim庐) and sodium stibogluconate (Pentostam庐). It is not completely understood how these drugs act against the parasite; they may disrupt its energy production or trypanothione metabolism. Unfortunately, in many parts of the world, the parasite has become resistant to antimony and for visceral or mucocutaneous leishmaniasis,[2] but the level of resistance varies according to species.[3] Amphotericin is now the treatment of choice[4]; failure of AmBisome庐 to treat visceral leishmaniasis (Leishmania donovani) has been reported in Sudan,[5] but this failure may be related to host factors such as co-infection with HIV or tuberculosis rather than parasite resistance.
Miltefosine (Impavido庐), is a new drug for visceral and cutaneous leishmaniasis. The cure rate of miltefosine in phase III clinical trials is 95%; Studies in Ethiopia show that is also effective in Africa. In HIV immunosuppressed people who are coinfected with leishmaniasis it has shown that even in resistant cases 2/3 of the people responded to this new treatment. Clinical trials in Colombia showed a high efficacy for cutaneous leishmaniasis. In mucocutaneous cases caused by L.brasiliensis it has shown to be more effective than other drugs. Miltefosine received approval by the Indian regulatory authorities in 2002 and in Germany in 2004. In 2005 it received the first approval for cutaneous leishmaniasis in Colombia. Miltefosine is also currently being investigated as treatment for mucocutaneous leishmaniasis caused by L. braziliensis in Colombia,[2] and preliminary results are very promising. It is now registered in many countries and is the first orally administered breakthrough therapy for visceral and cutaneous leishmaniasis.[6](More, et al, 2003). In October 2006 it received orphan drug status from the US Food and Drug administration. The drug is generally better tolerated than other drugs. Main side effects are gastrointetinal disturbance in the 1-2 days of treatment which does not affect the efficacy. Because it is available as an oral formulation, the expense and inconvenience of hospitalisation is avoided, which makes it an attractive alternative.
More info here:
http://en.wikipedia.org/wiki/Leishmanias... No this is not the best answer because this person just did a search and came of with all of the technical traditional information as I could do and gave me no real help. Report It
This answer was bullshit. I thought the other answer was more help and more of a answer. If I wanted the textbook I could just do a google search. Report It
For the skin infection a 20-day course of sodium antimony gluconate (ie, sodium stibogluconate).
Resistant cases are treated with amphotericin.
This is a parasite that is endemic in places like India and South America. Treatments depend on where you contracted it and where you're infected.(skin or abdomen)
Sodium stibogluconate is the drug of choice in the US.
The best doctor would be a specialist in tropical medicine. |