What is Klinefelter鈥檚 Syndrome ?

its an extra x gene in a male it usually makes them sterile and a bit effeminate, slim and soft not having much body hair, or short and round with breast growth , they latter can also have female problems like breast cancer and osteoporosis. it can also affect speach in some males.

Klinefelter's syndrome is found in approximately 1 of 700 men, i.e. there are approximately 3600 boys and men with Klinefelter's syndrome in Denmark with 5 million inhabitants. Men usually have but one X and one Y chromosome, i.e. the chromosomeconstitution 46,XY. Men with Klinefelter's syndrome have more than one X chromosome, usually two X chromosomes, i.e. the chromosome constitution 47,XXY.
At birth the testicles of Klinefelter boys are of normal size. When the testicles grow quickly in boys with normal chromosomes at the age of 11-12 years, the testicles of Klinefelter boys stay very small, as a rule only 2 cms. from pole to pole. Usually only few sperms are developed in the testicles, and men with Klinefelter's syndrome are as a rule infertile. Boys with Klinefelter's syndrome should be treated with testosterone, usually from the 11 or 12 years of age, best with Restandol tablets (Testosteroneundecanoat), which does not affect the liver, or with injections of other testosterone preparations.

Klinefelter boys more often than other boys have delayed motor function, speech, and maturation development, which does not make them patients demanding special treatment. It is important that these boys at an early age go to a good day-care institution, and that there is a close cooperation between parents and day-care institution staff. If the speech development is delayed, it is important to get help from a speech-therapist for a period. Regarding the motor function development, the participation of parent/child in sports activities and group activities of any kind is of great value. The same is the case with regard to stimulating the delayed development in maturation. In this connection it must be mentioned, that it is also important to stimulate these boys to independence, and not in any way to overprotect them.

Regarding the missing muscle development in puberty and late puberty, with increased tiredness and need for sleep, this can to a great extent be counteracted, and usually quite eliminated, by relevant testosterone treatment from the age of 11- 12 years. For better muscle development and motor function it is of great importance to take part in different sports activities through childhood.

If Klinefelter boys grow up in a good, stable, and stimulating environment, the intelligence will be inside the normal area, though a little displaced, so that there are fewer than expected with an IQ over 110, but no increased frequency of boys with an IQ below 90. In a group of adult danish men with Klinefelter's syndrome an average IQ of 108 was found in comparison with 115 in a control group. use the online version. However, all persons with Klinefelter's Syndrome, or their parents, can order the printed version free of charge from the Turner Center.