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Why are women carriers for the disease hemophilia and men are not? |
Why are women carriers for the disease hemophilia and men are not? Hemophilia A and B apparently hemophilia is linked to the X chromosome. Females possess two X-chromosomes, whereas males have one X and one Y chromosome. Since the mutations causing the disease are recessive, a woman carrying the defect on one of her X-chromosomes may not be affected by it, as the equivalent allele on her other chromosome should express itself to produce the necessary clotting factors. However the Y-chromosome in men has no gene for factors VIII or IX. If the genes responsible for production of factor VIII or factor IX present on a male's X-chromosome is deficient there is no equivalent on the Y-chromosome, so the deficient gene is not masked by the dominant allele and he will develop the illness. males have XY chromosomes Because men have and XY and the Y doesnt carry much, if anything. And since women pass the X on to the boy and the boy's Y can't cover up for the hemophilia gene, boys get it. |
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there are some disorders that are equally popular within all races and ethnicities. try finding a credible website for more info on that though ...I have a 7 yr. old son with Hemophilia and we have had the pleasure of meeting MANY adults over the years that are still living with the disease. Ironically, I have a long time family friend that ... why Michigan? The internet lets us communicate world over! Let the world help you! Focus on the Feminine : Programs and Services : Hemophilia ...HFA Focus on the Feminine Chat Room and Bulletin ... 1. All races and economic groups are affected equally. 2. Everyone inherits two sex chromosomes, X and Y, from his or her parents. A female inherits one X chromosome from her mother and one X chr... It is a sign of anemia, its called pica. Not everyone who crunches ice is anemic though, some people just get into a habit. ...no but GL it is funny i thought people wouldnt be here to answer today is christmas go away! happy christmas ...If the child has type A or B hemophilia.... genotype B, unless there is a spontaneous gene mutation. Hemophilia A: The most common type, is caused by lack of enough clotting factor VII. Hemophi... hi sorry to hear about yr nephew. haemophilia is in our family my 2 uncles have it and my dad had colour blindness which is related to it. these things are genetically passed from the male suffere... |
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