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Are Carriers of hemochromatosis at risk of the illness or does it skip to the next generation?


My nephew is a carrier and he has been complaining of most of the symtoms that go with the disease (his father had it)

There is no straight answer to that because there is more than gene involved.

Of the two major types of hemochomatosis, you would have to have one bad gene from each parent to manifest symptoms.

It has been suggested that the offspring of two carriers, one of each type, would have symptoms.

There are other rare types.

There is a really good explanation of the genetics of hemochromatosis on Wikipedia. Check the link.

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