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Does the drug Adipex cause heart valve disease?


(Phentermine is Adipex)....The most recent study was in 1990 which combined phentermine with fenfluramine or dexfenfluramine and became known as Fen-Phen.

Although Fen-Phen was never approved by the FDA the agency did approve of the drug. A study was published in 1992 that Fen-Phen was more effective than diet and exercise with few side effects. However, in 1997 after 24 cases of heart valve disease in Fen-Phen users, fenfluramine and dexfenfluramine were voluntarily taken off the market at the request of the FDA. Studies later proved that nearly 30% of people taking fenfluramine of dexfenfluramine had abnormal valve findings. The FDA did not ask manufacturers to remove phentermine from the market.

So are there any know cases of Adipex(phentermine) causing heart valve disease?

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