My hdl is 15.6,ldl is 80 is it safe?

Your ratio, from those numbers is basically over 5....Generally speaking, anything over 4.5 is considered an indication of increased risks for heart disease.... The following information below is a further (good) discussion of ratio vs. total...

As I noted at the bottom though, there is also some increasingly strong considerations being focused on Triglycerides as being a significant indicator for heart disease....

All the best!!!!!
______________________________________...

1) Which is the biggest indicator of problems or risk?
* The Total Cholesterol number or,
* The ratio of LDL/HDL

Both are associated with cardiac risk. However, the LDL/HDL ratio is
a bigger indicator. The components of a measured total cholesterol
(LDL, HDL, triglycerides) includes HDL ("good" cholesterol) which
correlates inversely with cardiac risk.

From Best Practice of Medicine:
"Although useful in screening large populations for dyslipidemias,
serum cholesterol cannot be considered the sole measure of risk for
CHD attributable to serum lipids. This is based on our current
understanding of lipoprotein cholesterol subfractions and the
availability of standardized laboratory methods to measure them in
clinical practice. Serum total cholesterol tends to index
low-density-lipoprotein (LDL) cholesterol, which varies directly with
CHD risk (Figure 6) and is considered atherogenic.
High-density-lipoprotein (HDL) cholesterol varies inversely with CHD
incidence and is considered anti-atherogenic or protective."
http://merck.micromedex.com/bpm/bpm.asp?...

Here is a definition of the LDL/HDL ratio:
"Another ratio is LDL/HDL. The LDL/HDL ratio is actually a more pure
ratio than total cholesterol/HDL. Because LDL is a measure of bad
cholesterol and HDL is a measure of good cholesterol, whereas the
total cholesterol is the sum of HDL, LDL, and the VLDL. Yes, adding up
the HDL, LDL and VLDL makes up the total cholesterol measurement."
http://my.cardiovalens.com/featured/feat...

The data from studies suggests that the LDL/HDL ratio is more
predictive of cardiac risk:
"Data from the Lipid Research Clinics and the Framingham Heart Study
suggest that the total cholesterol (or
LDL-cholesterol)-to-HDL-cholesterol ratio may have greater predictive
value for CHD than serum total or LDL-cholesterol . . . In contrast,
serum total or LDL-cholesterol did not add independent predictive
value to the ratio." (1)

2) How is the Total Cholesterol number calculated?

This is derived from the Friedewald formula for LDL cholesterol:
LDL-cholesterol = Total cholesterol - (triglycerides/5) -
HDL-cholesterol

Thus, doing some basic algebra:

Total cholesterol = LDL-cholesterol + HDL-cholesterol +
(triglycerides/5)


But there is a growing concern about Triglycerides as being a more accurate predictor of future heart disease.....
From Best Practice of Medicine:
"Data from several studies, including the Framingham Study, suggest
that serum triglycerides may be important predictors for CHD in men or
women, but not consistently in both sexes. Despite these observations,
the current consensus holds that elevated levels of serum
triglycerides represent a risk marker for obesity, glucose
intolerance, and low HDL levels, all of which confer risk for CHD and,
to the extent possible, deserve preventive attention."
http://merck.micromedex.com/bpm/bpm.asp?...