Graves disease why does this cause a "staring appearance? biologically?

-The cause of the disease is unknown so symptoms of the disease are probably not explainable biologically.

Graves' disease can cause swelling of tissues around the eyes, which creates a characteristic "staring" or "frightened" appearance. The eyes bulge out and the eyelids appear to be pulled back. There is less blinking. The person may have double vision, itching and weeping.

http://www.intelihealth.com/IH/ihtIH/WSI...
http://www.ngdf.org/

Check out the history here:

http://www.bbc.co.uk/dna/h2g2/A688241

By the way - if you want to add as a contact, it would help if you allowed email - have added you but cannot contact you

Graves disease is the old name for a type of thyrotoxicosis. It can produce the staring eyes, called exopthalmus, even before other signs of over-activity occur. The effect is thought to be due to high levels of LATS Long acting thyroid stimulator. This causes inflammatory exudates in the retro orbital tissues, ( inflammation behind the eye) pushing it forwards.

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