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I am doing an essay on gene therapy focusing on adenovirus. What diseaes are targeted using adenovirus?


I am planning to include the most popular cystic fibrosis, but other than that ...i should include at least 2 other diseases that use adenovirus are a vector in gene therapy. I wanted something less common ....maybe not monogenetic diseases as CF is already one. Anyone has any suggestions of what kind of interesting disease i can include??

Duchenne Muscular Dystrophy is another one.
Gutted or "Stealth" adenoviral vectors have been used to introduce truncated micro-dystrophin clones into mdx mice allowing them to form the dystrophin-glycoprotein complex that is nonfunction in DMD patients. It's a promising approach for gene therapy treatment of the devastating disease.

Adenoviral vectors are also being used for gene therapeutic treatments of some cancers. That might be good since it's more of a developed disease rather than inherited disease. I think they've been used as "suicidal" vectors as an effective treatment for brain tumors.

Hopefully this helps.

Please see the webpages for more details on Adenoviruses and Cystic fibrosis. I suggest Fibromyalgia and Multiple sclerosis.
Please note that I am not a medical professional.

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