Gene therapy?

What is the future of gene therapy and I want more information on antigene and antisense therapy.

Theoretically, gene therapy is the permanent solution for genetic diseases. But it is not as simple as it appears since gene therapy has several inbuilt complexicities. Gene therapy broadly involves isolation of a specific gene, making its copies, inserting them into target tissue cells to make the desired protein. The story does not end here. It is absolutely essential to ensure that the gene is harmless to the patient and it is appropriately expressed. Another concern in gene therapy is the body鈥檚 immune system which reacts to the foreign proteins produced by the new genes.
The public, in general, have exaggerated expectations on gene therapy. The researches, at least for the present, are unable to satisfy them. As per the records, 1000 Americans had undergone clinical trails involving various gene therapies. Unfortunately, the gene therapists are unable to categorically claim the gene therapy has permanently cured any one of these patients. Some people in the media have openly questioned whether it is worth to continue research on gene therapy!!
It may be true that as of now, gene therapy due to several limitations has not progressed the way it should, despite intensive research. But a break-through may come anytime, and of course, this is only possible with persistent research. And a day may come when almost every disease will have a gene therapy, as one of the treatment modalities. And gene therapy will revolutionize the practice of medicine!