How does ESRD lower hemoglobin?

I know that bleeding does and so does a bone cancer or desease, but how does kidney failure do it? I am on hemodialysis and I am getting epogen for anemia.

It lowers hemoglobin because the production of erythropoetin, which is normally produced by the kidney, is reduced significantly in renal failure. Erythropoetin stimulates production of red blood cells. Epogen is a recombinant DNA form of human erythropoetin.

I'm sorry but the above answer is correct. I was a dialysis nurse for almost 3 yrs.

your kidneys produce a hormone called erythropeiten (spelling could be off) . this hormone helps produce red blood cells (blood) . when kidneys no longer function you need a synthetic form of the hormone so that you body can continue to produce it's own red blood cells (epogen is the synthetic for of erythropoeitin)

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