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Streptomycin how does affect ears does it cause deafness and tinitus? |
Streptomycin how does affect ears does it cause deafness and tinitus? Streptomycin is an aminoglycoside antibiotic, and this group can cause cohlear damage and deafness Streptomycin stops bacterial growth by damaging cell membranes and inhibiting protein synthesis. Specifically, it binds to the 16S rRNA of the bacterial ribosome, which prevents the release of the growing protein (polypeptide chain). Humans have structurally different ribosomes than bacteria, thereby allowing the selectivity of this antibiotic for bacteria. Streptomycin cannot be given orally, but must be administered by regular intramuscular injection. An adverse effect of this medicine is ototoxicity. It can result in permanent hearing loss. My dad contracted TB in the early sixties and just about at that time Streptomycin was discovered as the new wonder drug for the disease. He was in hospital for a long time and this drug was given to him. As far as I know, he did not suffer any ill-effects as you mention during or after treatment. Don't know if this helps you, but hope it does. |
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