Can elevated liver enzymes be normal?

I am a 30 yr old female with elevated liver enzymes. They have been elevating from high to very high. I went in for a physical about 2 years ago and found they were still high. I had another biopsy, ultrasound, and other tests ruling out Hepatitus, some autoimmune diseases, biliary problems, ect. What is wierd is that my sister also has these elevated enzymes. My dad had 2 liver transplants because of Hep. C, but as I said before that was not found in me. I have extreme fatigue all of the time, and recently my right had started to become numb. It's the top of the hand and is now working it's way up the arm. I also had Cholostasis of Pregnancy when I was preganant with my daughter. I have no idea if any of it is related. My doctor doesn't seem to be to concerned and says that it could be that I just have high liver enzymes. I'm having blood tests done every 3 months now to watch them, but they continue to stay high.

There are things that we can come across in our daily lives (medications and alcohol, viruses, etc) that can give us elevated liver enzymes which will just settle and resolve by themselves.

If they continue to stay elevated, perhaps your doctor should continue the search for the reason, though. You may require a referral to a liver specialist (often a gastroenterologist) and perhaps even a liver biopsy!

The fatigue is suggestive of a viral or an autoimmune condition.

Your doctor may be right. Your enzymes may be elevated due to heredity. That your sister also has elevated enzymes may be supporting evidence of this.

Your cholestasis of pregnancy probably had more to do with pregnancy hormones than anything else. Find out what the fatigue and numbness may be related to. Any pinched nerves? An unusual amount of stress in your life? Any other health issues? Be sure to follow up on these symptoms.