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What causes an acoustic neuroma? What can make it go away other than radiation or surgery? Like medicine?


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Mobile phone use and acoustic neuroma risk in Japan

Objectives: The rapid increase of mobile phone use has increased public concern about its possible health effects in Japan, where the mobile phone system is unique in the characteristics of its signal transmission. To examine the relation between mobile phone use and acoustic neuroma, a case-control study was initiated.

Methods: The study followed the common, core protocol of the international collaborative study, INTERPHONE. A prospective case recruitment was done in Japan for 2000鈥?4. One hundred and one acoustic neuroma cases, who were 30鈥?9 years of age and resided in the Tokyo area, and 339 age, sex, and residency matched controls were interviewed using a common computer assisted personal interview system. Education and marital status adjusted odds ratio was calculated with a conditional logistic regression analysis.

Results: Fifty one cases (52.6%) and 192 controls (58.2%) were regular mobile phone users on the reference date, which was set as one year before the diagnosis, and no significant increase of acoustic neuroma risk was observed, with the odds ratio (OR) being 0.73 (95% CI 0.43 to 1.23). No exposure related increase in the risk of acoustic neuroma was observed when the cumulative length of use (<4 years, 4鈥? years, >8 years) or cumulative call time (<300 hours, 300鈥?00 hours, >900 hours) was used as an exposure index. The OR was 1.09 (95% CI 0.58 to 2.06) when the reference date was set as five years before the diagnosis. Further, laterality of mobile phone use was not associated with tumours.

Conclusions: These results suggest that there is no significant increase in the risk of acoustic neuroma in association with mobile phone use in Japan.

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Medical therapy: Acoustic neuromas are managed in one of 3 ways, (1) surgical excision of the tumor, (2) arresting tumor growth using stereotactic radiation therapy, or (3) careful serial observation.

Observation: Simple observation without any therapeutic intervention has been used in the following groups of patients:

1) Elderly patients

2) Patients with small tumors, especially if their hearing is good

3) Patients with medical conditions that significantly increase the risk of operation

4) Patients who refuse treatment

5) Patients with a tumor on the side of an only hearing ear or only seeing eye

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