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Explain why an Rh-negative person does not have a transfusion reaction on the first exposure?


Explain why an Rh-negative person does not have a transfusion reaction on the first exposure to Rh-positive blood but does have a reaction on the second exposure. What happens when an ABO blood type is mismatched for the first time?

the body has to build antibodies. On first reaction the body has no antibodies, however on second reaction the body has had time to build antibodies to that rh negative.

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